Dengue Fever Vaccine: Who Needs It, What the Injection Involves, and Which Countries Require It

Yes, a dengue fever vaccine is now available in the UK, and for the right traveller it can be a useful extra layer of protection. Qdenga is licensed for use in people aged four and over, but it is not suitable for everyone, and it is not funded on the NHS for travel purposes.
What Is the Dengue Fever Vaccine and How Does It Work?
The UK-licensed dengue vaccine is called Qdenga. It is a live, weakened vaccine designed to trigger an immune response against all four dengue virus strains, known as DENV-1 to DENV-4.
It is given as two doses, three months apart, so it needs to be planned well in advance of travel rather than booked at the last minute. Because dengue itself has no specific cure, the NHS confirms that prevention, whether through vaccination or avoiding mosquito bites, remains the main way to reduce your risk.
Who Should Consider the Dengue Vaccine?
The vaccine is mainly recommended for travellers who have previously had dengue, or who may have been exposed before, and who are returning to a country where the virus is common.
If You Have Had Dengue Before
A second dengue infection carries a higher risk of severe illness. If you know or suspect you have had dengue on an earlier trip, this is the group the vaccine is most clearly aimed at, and it is worth raising at your travel consultation.
If You Have Never Had Dengue
Current guidance from the Joint Committee on Vaccination and Immunisation is more cautious here. There is not yet enough clinical evidence to routinely recommend the vaccine for travellers with no previous dengue exposure, so this is assessed individually rather than offered as a blanket recommendation.
Which Destinations Carry the Highest Dengue Risk?
Dengue is most common across:
- South and Southeast Asia, including Thailand, Vietnam and Indonesia
- The Indian subcontinent
- The Caribbean and parts of Central and South America
- Parts of sub-Saharan Africa
- Increasingly, parts of southern Europe during the warmer months
You can check destination-specific risk on TravelHealthPro, the UK’s official travel health resource, before you travel, and this should form part of any pre-trip consultation.
How Is the Dengue Vaccine Given, and When Should You Book?
Qdenga is given as two injections spaced three months apart, so ideally you should start the course at least three to four months before departure. It cannot be compressed into an accelerated schedule the way some other travel vaccines can.
If your trip is closer than this, a consultation is still worthwhile. A pharmacist can advise on partial protection, mosquito bite prevention, and any other vaccines or medication you may need for your destination.
What Are the Side Effects and Who Should Avoid the Vaccine?
As with most vaccines, common side effects include soreness at the injection site, headache, muscle aches and mild fatigue, which usually settle within a few days.
Because Qdenga is a live vaccine, it is not suitable for everyone. It is not recommended for:
- People who are pregnant or breastfeeding
- People with a weakened immune system
- Anyone with a known allergy to a vaccine ingredient
A full medical history is taken at your consultation so your pharmacist can confirm whether the vaccine is appropriate for you.
Beyond the Vaccine: How Else Can You Reduce Your Risk?
Even with vaccination, mosquito bite avoidance remains essential, since no vaccine offers complete protection. This means:
- Using a DEET or picaridin-based repellent, reapplied regularly
- Wearing long sleeves and trousers, particularly during the day, when dengue-carrying mosquitoes are most active
- Sleeping under a net where accommodation is not fully screened
- Keeping windows and doors closed or screened where possible
If you feel unwell with a high fever during or after travel to a dengue-affected area, seek medical advice promptly and mention your travel history.
Book a Dengue Vaccine Consultation at Ham Pharmacy Group
If you are travelling to a dengue-risk destination, our travel clinic team can assess whether the dengue vaccine is right for you, alongside any other travel vaccinations or anti-malarial medication your trip may need. We also cover related mosquito-borne risks such as chikungunya, which is worth discussing if you are visiting the same regions.
Heading to Central or South America? Our regional vaccine checklist covers dengue alongside yellow fever, malaria and other destination-specific risks.
Sine the dengue course takes three months to complete, the earlier you book, the more protection options remain available to you. Book your travel health consultation with Ham Pharmacy Group today.
Frequently Asked Questions
No. It is available privately through travel clinics and pharmacies, including Ham Pharmacy Group.
Pricing varies by provider and dose count. Your pharmacist can confirm current pricing at your consultation.
It is not generally recommended for pregnant or breastfeeding people, those with a weakened immune system, or anyone allergic to an ingredient. Those with no previous dengue exposure should discuss suitability with a pharmacist.
Ideally three to four months, as the two doses are given three months apart. If your trip is sooner, a consultation can still cover partial protection and bite prevention.
Common symptoms include high fever, severe headache, joint and muscle pain, nausea, and a rash. Most cases resolve within days but seek urgent care if warning signs appear.
Yes. There are four dengue strains, and a second infection carries a higher risk of severe illness.